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All street drugs are chemicals that will affect your brain if you take them.
Missing your insulin puts you at risk of DKA. If you are feeling confused you might not be able to tell if you are hypo or may not deal with your hypo correctly.
Taking drugs such as ecstasy at parties can put you in situations of real danger and can kill you. Ecstasy gives you a false feeling of having lots of energy and you can do things that would normally tire you out. This can cause your body to overheat and become dehydrated. You could have a hypo severe enough to cause you brain damage.
Mixing drugs or mixing alcohol and drugs can be lethal.